Pitfalls in CTP: Why CTP Isn’t Always the Holy Grail in Acute Stroke Imaging

March 8, 2022
CTP is alluring in acute stroke and continues to become more available. But it's complicated. Learn the pitfalls and traps from a true expert in perfusion imaging.
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When Should We Consider Restarting Anticoagulation in DVT, PE and Afib Patients? What Should I Tell the Family To Be on the Look-Out for Once They Are Discharged?

February 1, 2022
When patients need anticoagulation but have had an ICH or large ischemic stroke, when do we restart anticoagulation? When, if ever, is it safe?  
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What Key Lessons Have I Learned Managing Hemorrhagic Bleeding in the ICU & Critical Care?

January 25, 2022
Intracerebral hemorrhages are challenging to manage and patients need immediate interventions to preserve life and limit morbidity. Lessons learned from the ICU and ED shed light on how to best care for these patients.
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A Review of the Different Types of Anticoagulants and Their Clinical Applications

January 18, 2022
Anticoagulation in clinical practice is more common and more complicated every day. Understanding what they are, how they're used and when you'll see them in the clinical arena is critical. Two experts discuss their understanding of the landscape of anticoagulation and what you need to know about it.
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Why Is the Extended Window Controversial and What Happened With the FDA?

September 7, 2021

Ever wonder why the FDA didn't approve the extended time window for tPA after ECASS3? Listen here to understand the discussion.

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Dec 4

What Was Missing From the NINDS Trial?

Brian Gibler posted on 12/4/2020

Moderator: Jordan Bonomo, MD, FCCM, FNCS
Other Participants: Opeolu Adeoye, MD, MS FACEP, FAHA

The NINDS trial was the seminal study of IV-tPA in the treatment of acute stroke. Yet controversy still exists around the trial methodology and the interpretation of the data. Was anything missing from NINDS? Does it still resonate nearly 25 years later?

Dr. Opeolu (Ope) Adeoye sits down with Dr. Jordan Bonomo and shares his immense expertise in clinical trialing. As a researcher carrying over $30M in research funding, Dr. Adeoye is an internationally recognized stroke trialist and methodologist. In this podcast, he talks about the challenges of the NINDS trial, what was really well done and what could have been different. “Time critical diagnosis” is the term he wields in this exciting and thought provoking podcast.

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