Endovascular Strategies for Acute Strokes in the Era of COVID - What Changes?

November 30, 2020
COVID-19 patients with acute strokes present unique management challenges; listen to the lead author of a manuscript about endovascular standards of care in COVID stroke discuss strategies and techniques for neurointervention in COVID.
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The Future of Mobile Stroke Units – The Frontier is Here…

November 12, 2020
In today’s technology-savvy world, we have come to expect getting goods and services delivered on demand and on our terms. We want things right away. The concept of having to wait for something is somewhat frowned down upon.
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Sep 7

Why Is the Extended Window Controversial and What Happened With the FDA?

Haemin Go posted on 9/7/2021

Moderator: William A. Knight IV, MD, FACEP, FNCS
Other Participants: Stacie L. Demel, DO, PhD

The ECASS 3 trial was an RCT of IV-rtPA in the window of 3-4.5 hrs after onset of stroke symptoms. It was conducted in Europe. The European regulatory bodies have endorsed tPA for that window, but the FDA has not. Listen to two national experts in stroke discuss the trial and the meaning of the endorsement or lack thereof. This podcast is a must for acute stroke practitioners!

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2 comments on article "Why Is the Extended Window Controversial and What Happened With the FDA?"

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Ken Milne

I watched the video on ECASS-III and you mentioned the controversy in this time window. However, there was no mention of Alper et al reanalysis in the BMJ_EBM that questioned the results? Can you comment? https://ebm.bmj.com/content/25/5/168


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Ken Milne

Here was some of our feedback on Alper et al https://ebm.bmj.com/content/early/2020/08/10/bmjebm-2020-111517
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